Last Updated: March 23, 2020
Editor's Choice


Last Updated: March 28, 2020

Background Check

Cognifen is an another brain enhancement that aspires to garner attention and a loyal following in the nootropic world. Acording to its product copy, it’s an all-natural option to tackle brain health, which can start to decline or experience issues with aging. It proposes nourishing the brain as one important key of holistic wellness.

It comes in a supposedly all-natural, vegetarian-friendly capsule in a 30-day supply per bottle. The recommended dose is 2 capsules taken once daily.

Formula Highlights

Supplement Facts

Key Ingredients

Here is the ingredient lineup for Cognifen and their respective potential benefits:


  • Acetyl-L-Tyrosine– Hailed as a potent brain booster, increases metabolic energy for greater mental alertness, and helps reduces fatigue.
  • Alpha Lipoic Acid– Essential to ATP energy production in the brain in order to help neurons maintain optimal energy levels.
  • Brahmi (Bacopa Monnieri)– Useful in improving information processing and speed for enhanced brain function, memory, and concentration.
  • Choline Bitartrate– Improves levels of choline, which in turn increases acetylcholine production for raising nerve membrane fluidity.
  • DHA Omega 3 Amino Acids– Promotes better blood flow to enhance cognition, brain function, and memory.
  • DMAE– Boosts levels of choline, in turn raising acetylcholine production for better nerve membrane fluidity.
  • Green Tea Extract– Ups the activity of the inhibitory neurotransmitter GABA, holding anti-anxiety effects. It increases dopamine and the production of alpha waves in the brain as well.
  • Huperzine A– Increases general cognitive function, particularly memory, cognition, and behavioral markers.
  • Phosphatidylserine– Crucial to support brain neurons, maintain memory function, and improve neuroplasticity.
  • Vitamin B Complex Blend– Supports healthy blood flow, oxygenation, as well as energy production in the brain. This is made up of Vitamin B1 (Thiamin), Vitamin B2 (Riboflavin), Vitamin B3 (Niacin), and Vitamin B6.

Cognifen is made up of a balanced roster of nootropic ingredients, both proven compounds in food and in plants. These are ingredients we’ve already seen before but haven’t lost their luster and effectiveness in brain boost and enhancement.


Rating: 16/20

Effects and Benefits

Cognifen is designed for supporting mental flexibility, or enhancing life-long cognitive ability for faster learning. Notice the use of “life-long,” implying that the product will continue to provide benefits no matter what (even when you stop supplementation?). It also targets a boost in memory, stress reduction, and overall improvement in focus.

There are purported benefits on raising metabolic energy, which translates to better mental alertness and reduced fatigue. These cover so many bases, and it now boils down to the dosing and purity of extracts to get the desired effects. Our reservation, however, is that the benefits might be as quick to manifest as promised.

Rating: 16/20

Potential Side Effects

General warnings apply to Cognifen as well, such as those under the age 18 or pregnant/lactating women needing to consult their doctor before taking the supplement. We didn’t find a lot of side effect reports online, and this is a great plus point for Cognifen especially if a customer puts a premium on safety.

Rating: 18/20

Pricing Options

A one-month supply of Cognifen sells for $49 on its official website. There are, however, 1 and 3 pack options on other sites such as Amazon. This is relatively expensive for a nootropic and can be offset through more price-friendly bundles or a working money-back guarantee.

Rating: 13/20

Online Reviews

Cognifen has 26 customer reviews on Amazon as of this writing, and that limited number is a real problem if we’re going to look for trustworthiness and reliability. While others note that it does work and quell their doubts at the beginning, there are reviews that point to dissatisfaction. According to some, it “did not work as indicated,” “doesn’t do much,” and “caused severe stomach cramps and bowel issues,” prompting the user to send back and ask for refund. The combination of the limited numbers of reviews and the negative feedback doesn’t bode well for a nootropic that’s supposed to be trusted by its users.

Rating: 11/20



  • Generally fares well on safety and side effects
  • Transparency in ingredient list
  • No outrageous claims in effects and benefits


  • Relatively costly
  • Lack of clinical or third-party research to vouch for benefit claims
  • Lack of reliable online reviews and testimonials

Our Verdict

Cognifen is good at making a single marketing hook: A clean, reliable, no-frill brain supplement to help your cognition, focus, and memory see better days. It’s something you might want to take advantage of if you’re having related issues, and it helps that the ingredients are widely recognizable and generally regarded safe.

But there must be something else to appreciate than just the basics if a nootropic product is going to be priced at $49 for a bottle. It has to show so much more strength, rigor in its clinical findings, and differentiator in a cutthroat marketplace – something Cognifen fails to provide, even with a seeming reformulation.

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